The Patient-Centered Outcomes Research Institute (PCORI) is seeking applicants for Phase II funding totaling up to $150.7 million in its bid to build a "network of networks" for comparative effectiveness research.
It plans to award up to $82.7 million to clinical data research networks (CDRNs) for access to the data of at least 1 million patients. PCORI will pay for $8.75 million in direct costs for up to 13 networks over a three-year period.
These networks must work to capture the complete healthcare data on this population, including electronic health record data from both ambulatory and inpatient care within a delivery system and claims data or other information reflecting care received outside the delivery system, according to its plan.
PCORI is seeking both Phase I and new applicants.
In addition, it's offering up to $1.68 million in total costs for 22 Patient-Powered Research Networks (PPRNs) over three years.
Both types of networks must become capable of supporting randomized and observational CER studies, rapid-cycle studies, and other types of health research using robust standardized data sets with strong patient privacy and security protections, according to an announcement. In addition, they're expected to boost collaboration and develop plans for sustaining operations after this funding ends.
Groups have until Jan. 15 to submit letters of intent to apply.
Eleven 11 CDRNs and 18 PPRNs were funded in Phase I. The National Pediatric Learning Health System from the Children's Hospital of Philadelphia was among the CDRNs funded in the first round, in which healthcare organizations pool information from various data sources including electronic health records.
The PPRNs included the Epilepsy Foundation's Collaborative Patient-Centered Rare Epilepsy Network and the American BRCA Outcomes and Utilization of Testing Patient-Powered Research Network (ABOUT Network) at University of South Florida.
Technology projects were among those awarded $54.8 million in PCORI funding in August.